Postbiotics are the latest evolution in gut health supplements, consisting of beneficial compounds produced by probiotic bacteria (like short-chain fatty acids, enzymes, and peptides) or heat-treated bacterial cells. Unlike live probiotics, postbiotics are shelf-stable, don't require refrigeration, and offer immune and digestive benefits without viability concerns.
Supports immune system function
Promotes digestive health and gut barrier
Shelf-stable (no refrigeration required)
May reduce digestive discomfort
Supports healthy inflammatory response
Suitable for immunocompromised individuals (no live bacteria)
Not all dosage forms are created equal. Here are the most effective formats for postbiotics supplements based on bioavailability and consumer preference.
Versatile delivery system ideal for powder-based formulations with rapid absorption.
Learn moreVersatile format offering customizable dosing and rapid nutrient delivery.
Learn moreEnjoyable supplement format that combines nutrition with a pleasant taste experience.
Learn moreRecommended Daily Dose:
Varies by ingredient - typically 250-500mg postbiotic metabolites or heat-treated cells per serving
Typical Product Strength:
Capsules: 250-500mg; Powders: 500-1000mg per scoop; Gummies: 250mg
Common Serving Sizes:
30-60 capsule bottles, 30 serving powder containers, 60 gummy bottles
Major advantage - highly stable compared to live probiotics. Heat-treated bacterial cells or purified metabolites (butyrate, etc.) have 24-36 month shelf life at room temperature. No refrigeration required.
Metabolites like butyrate (short-chain fatty acid) are directly bioactive. Heat-killed cells (paraprobiotics) interact with immune system. May require enteric coating for targeted delivery to colon.
Minimal taste for most postbiotic ingredients. Capsules preferred. Powders can be unflavored or lightly flavored. Gummies fruit-flavored.
Emerging ingredient category. Key suppliers include specialty fermentation companies. Common ingredients: CoreBiome (postbiotic metabolites), Lactobacillus plantarum L-137 (heat-killed), Butyrate (short-chain fatty acid). Quality and clinical backing vary.
1000 bottles (30,000-60,000 capsules)
Most manufacturers require 5,000+ units. Our 1,000-unit MOQ lets you start smaller and test the market without massive upfront investment.
4-6 weeks
Includes formulation finalization, production, quality testing, and packaging. Rush options may be available for additional cost.
Budget Tier
$20-28 (basic postbiotic formula)
Entry-level products, standard formulations
Mid-Range
$30-45 (clinically backed ingredients)
Higher quality, better absorption
Premium
$50-70+ (targeted formulas, combination products)
Pharmaceutical grade, patented forms
*Retail prices shown are market averages. Your costs will be significantly lower. Contact us for detailed manufacturing cost breakdowns.
Regulatory status evolving. Most postbiotic ingredients are GRAS or dietary ingredients. Structure/function claims allowed: "supports immune health", "promotes digestive wellness". FDA monitoring category as it develops.
NPN pathway available. Heat-killed probiotics and metabolites can be licensed. Claims depend on specific ingredient and clinical data. Emerging category - regulatory precedents being set.
Our Expertise: We've helped secure 92% NPN approval rate for Canadian products. Our team ensures your postbiotics formulation meets all regulatory requirements for both markets, from label compliance to permitted health claims.
These are the most successful postbiotics products in the market. We can help you create any of these formulations.
Next-gen category emerging as alternative to probiotics. Appeals to consumers who don't want live bacteria or refrigeration hassle. Science-backed but less consumer awareness currently. Expected to grow significantly as education increases.
Target Market: Health-conscious consumers 30-60, those who don't tolerate live probiotics, travelers, immunocompromised (with physician guidance), early adopters, 60% female
Consumer education (postbiotics vs. probiotics vs. prebiotics)
Limited ingredient suppliers (emerging category)
Higher raw material costs than commodity probiotics
Explaining benefits without live bacteria (counterintuitive)
Differentiating from probiotic market leaders
Our manufacturing partners have solved these challenges across hundreds of postbiotics products. We'll help you avoid common pitfalls and launch a high-quality, compliant product.
Our minimum order quantity is 1000 bottles (30,000-60,000 capsules). Most manufacturers require 5,000+ units, but our 1,000-unit MOQ lets you test the market without massive upfront investment. This makes postbiotics supplements accessible even for new brands.
Typical lead time is 4-6 weeks. This includes formulation finalization, ingredient sourcing, production, quality testing (including third-party COA), packaging, and labeling. Rush production may be available depending on facility capacity.
The best dosage form depends on bioavailability, consumer preference, and your target market. For postbiotics, we typically recommend:
Yes! We specialize in Canadian NPN applications with a 92% approval rate. For postbiotics products, we'll handle the entire submission process, from compiling evidence to responding to Health Canada inquiries. Typical NPN approval takes 6-12 months.
Manufacturing costs depend on dosage form, strength, packaging, and order quantity. At our 1,000-unit MOQ, typical total costs range from $8,000-15,000 including product manufacturing, packaging, testing, and compliance. We provide transparent pricing with detailed breakdowns. Contact us for a custom quote based on your specific requirements.
We offer both! If you want a standard postbiotics formulation, we can match you with proven stock formulas from our manufacturing partners (white label). If you want something unique, we create custom formulations tailored to your target market, combining postbiotics with complementary ingredients for enhanced benefits.
All postbiotics products include third-party Certificate of Analysis (COA) testing for:
All manufacturing partners are FDA-registered, GMP-certified facilities that follow strict quality protocols.
Our expert team will guide you through formulation, production, regulatory compliance, and everything you need to bring your postbiotics supplement to market in the US and Canada.